2017-10-022017-09-11SANTOS, Thiago Augusto Dias. Detecção fotoeletroanalítica de adrenalina baseada em DNA e nanopartículas de TiO2 sensibilizadas com Bis (Etilenoditio) tetratiofulvaleno explorando luz de led. 2017. 92 f. Dissertação (Mestrado em Química) - Universidade Federal do Maranhão, São Luís, 2017.https://tedebc.ufma.br/jspui/handle/tede/tede/1950A photoelectroanalytical sensor was developed, based on deoxyribonucleic acid (DNA) and anatase titanium dioxide (TiO2) nanoparticles sensitized with bis(ethylenedithio)tetrathiofulvalene (BEDT-TTF) for determination of the adrenaline, also denominated as epinephrine. The photosensor composite developed was denominated as BEDT-TTF/DNA/TiO2/ITO and shows a high photocurrent for the adrenaline under light emitting diode (LED) irradiation in comparison to each component of the composite material. Under optimized conditions, the BEDTTTF/DNA/TiO2/ITO sensor shows a linear response range from 10 nmol L-1 up to 100 μmol L-1 with a sensitivity of 8,1 nA L μmol-1 and limit of detection of 1 nmol L-1 for the adrenaline. The photoelectrochemical sensor showed high photocurrent to adrenaline in comparison to photocurrent response to ascorbic acid and uric acid. The BEDT-TTF/DNA/TiO2/ITO photoelectrochemical sensor was successfully applied to urine samples, with recovery values between 96 and 106%.application/pdfAcesso AbertoAdrenalinaSensor fotoeletroquímicoDiodo emissor de luz (LED) visívelÁcido desoxirribonucleicoAdrenalinePhotoelectrochemical sensorVisible light emitting diode (LEDDeoxyribonucleic acidQuímica AnalíticaDissertação